NIFTY®
Test Content

Everything that NIFTY® PRO screens for,in one place.

Powered by BGI genomics, NIFTY® PRO screens across all 23 pairs of chromosomes. Each sample is sequenced to a depth of 25M, increasing detection of microdeletions and microduplications. NIFTY® · BGI

  • Detects chromosomal disorders across 23 pairs of chromosomes.
  • 25M data per sample for greater micro-event sensitivity.
  • From week 10 of pregnancy, single small blood draw.
NIFTY® PRO Reassures You

Peace of mind, from a single blood draw.

Being pregnant is something every woman is extremely excited for — and naturally, you want to make sure your baby is healthy. Prenatal screening helps you understand whether your baby may have inherited a genetic condition. NIFTY® PRO uses the mother's peripheral blood to accurately assess the risk of Down syndrome and other chromosomal disorders, with no risk to mother or fetus.

23
Pairs of chromosomes screened
25M
Sequencing data per sample
84
Microdeletion / duplication syndromes
Technology

Genomics-grade sequencing, clinically validated.

An Emirati laboratory scientist operating a DNA sequencer
  • Blood sampling is safe, convenient, and entirely non-invasive.
  • High-throughput sequencing covering 95+18 tests and additional findings.
  • High-quality QC monitoring of cell-free fetal DNA concentration.
  • Clinically validated for twin pregnancies.

International certification

  • •International patented analysis — PCT/CN2011/001070
  • •50+ peer-reviewed international clinical papers
  • •Reported by in UAE
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Trisomies

The three most common autosomal trisomies.

Down Syndrome — Trisomy 21

Incidence · Risk increases with maternal age (age 35: 1/400).

Caused by an extra copy of chromosome 21. Most children have intellectual disabilities ranging from mild to moderate; early intervention is essential.

Sensitivity >99.99% · Specificity >99.97%

Edwards Syndrome — Trisomy 18

Incidence · 1 / 6,000

Three copies of chromosome 18. High risk of miscarriage; most babies do not survive beyond the first year. Severe intellectual disabilities and birth defects of the heart, brain, and kidneys.

Sensitivity >99.99% · Specificity >99.97%

Patau Syndrome — Trisomy 13

Incidence · 1 / 10,000 – 1 / 21,700

Three copies of chromosome 13. High risk of miscarriage or stillbirth; heart defects, brain or spinal cord problems, cleft lip/palate, and other birth defects are common.

Sensitivity >99.99% · Specificity >99.96%

NIFTY®Pro
Rare Autosomal Aneuploidies

Going beyond the basics with NIFTY PRO.

Available for singleton pregnancies only.

Trisomy 9

Incidence · Unknown

Full trisomy 9 is lethal in the first trimester. Mosaic trisomy 9 is associated with developmental delay, cardiac, neurological and skull dysmorphisms.

Rare — sensitivity not yet validated

Trisomy 16

Incidence · 32 / 100,000

Full trisomy 16 is lethal in the first trimester. Mosaic trisomy 16 carries increased risk of delayed growth and cognitive disorder.

Rare — sensitivity not yet validated

Trisomy 22

Incidence · 9 / 1,000,000 – 20 / 100,000

Full trisomy 22 is lethal in the first trimester. Mosaic trisomy 22 may cause intellectual disability, kidney malformation and imbalanced development.

Rare — sensitivity not yet validated

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Sex Chromosome Aneuploidies

X and Y chromosome conditions.

Available for singleton pregnancies only.

Turner Syndrome — 45,X (XO)

Incidence · 1 / 2,000 – 1 / 5,000

Completely or partially missing X chromosome in females. Common traits include shorter stature and underdeveloped ovaries leading to infertility.

Sensitivity >95%

Klinefelter Syndrome — XXY

Incidence · 1 / 500

An extra X chromosome in males. Small testes and low testosterone result in incomplete development of male sexual characteristics and infertility.

Sensitivity >95%

Triple X Syndrome — XXX

Incidence · 1 / 1,000

Additional X chromosome in females. Often asymptomatic; can include learning disabilities and delayed speech, language, or motor development.

Sensitivity >95%

XYY Syndrome

Incidence · 1 / 1,000

Extra Y chromosome in males. Affected individuals are typically very tall; may experience severe acne, learning difficulties, and impulsivity.

Sensitivity >95%

Gender Identification

Incidence · —

Singleton fetal gender identification.

>99%

Microdeletion & Microduplication

84 microdeletion and microduplication syndromes.

NIFTY® PRO's extended panel screens for sub-chromosomal events that standard NIPTs may miss — a more complete genomic picture from a single blood draw.

01Chromosome 1p31 duplication syndrome
02Chromosome 1p32-p31 deletion syndrome
03Chromosome 1p36 deletion syndrome
04Chromosome 1q41-q42 deletion syndrome
05Chromosome 2p12-p11.2 deletion syndrome
06Chromosome 2p16.1-p15 deletion syndrome
07Split-hand/foot malformation 5
08Chromosome 2q31.1 duplication syndrome
09Chromosome 2q31.1 deletion syndrome
10Chromosome 2q35 duplication syndrome
11Holoprosencephaly 6
12Chromosome 3pter-p25 deletion syndrome
13Chromosome 3q13.31 deletion syndrome
14Dandy-Walker syndrome
15Chromosome 3q29 deletion syndrome
16Chromosome 3q29 duplication syndrome
17Wolf-Hirschhorn syndrome
18Chromosome 4q21 deletion syndrome
19Chromosome 4q32.1-q32.2 triplication syndrome
20Cri-du-Chat syndrome
21Chromosome 5q12 deletion syndrome
22Chromosome 5q14.3 deletion syndrome
23Chromosome 6pter-p24 deletion syndrome
24Chromosome 6q11-q14 deletion syndrome
25Chromosome 6q24-q25 deletion syndrome
26CHDM
27Chromosome 7q deletion syndrome
28Chromosome 7q11.23 deletion syndrome
29Chromosome 7q11.23 duplication syndrome
30Chromosome 8p23.1 deletion syndrome
31Chromosome 8p23.1 duplication syndrome
32Chromosome 8q12.1-q21.2 deletion syndrome
33Chromosome 8q22.1 duplication syndrome
34Chromosome 8q22.1 deletion syndrome
35Langer-Giedion syndrome
36Chromosome 9p deletion syndrome
37DiGeorge syndrome 2
38Chromosome 10q22.3-q23.2 deletion syndrome
39Chromosome 10q26 deletion syndrome
40Potocki-Shaffer syndrome
41WAGR syndrome
42WAGRO syndrome
43Jacobsen syndrome
44Chromosome 12q14 microdeletion syndrome
45Chromosome 13q14 deletion syndrome
46Chromosome 14q11-q22 deletion syndrome
47Frias syndrome
48Chromosome 15q11-q13 duplication syndrome
49Angelman syndrome
50Prader-Willi syndrome
51Chromosome 15q14 deletion syndrome
52Chromosome 15q25 deletion syndrome
53Congenital Diaphragmatic Hernia (CDH)
54Chromosome 15q26-qter deletion syndrome
55Levy-Shanske syndrome
56Chromosome 16p deletion syndrome
57Chromosome 16p11.2-p12.2 microduplication syndrome
58Chromosome 16p12.2-p11.2 deletion syndrome
59Chromosome 16p13.3 deletion syndrome
60Chromosome 16q22 deletion syndrome
61Potocki-Lupski syndrome
62Smith-Magenis syndrome
63Yuan-Harel-Lupski syndrome
64Chromosome 17p13.3 duplication syndrome
65Chromosome 17p13.3 deletion syndrome
66Chromosome 17q12 deletion syndrome
67Chromosome 17q12 duplication syndrome
68Chromosome 17q21.31 duplication syndrome
69Chromosome 17q23.1-q23.2 deletion syndrome
70Chromosome 18p deletion syndrome
71Chromosome 18q deletion syndrome
72Chromosome 19q13.11 deletion syndrome
73Holoprosencephaly 1
74Cat-Eye syndrome
75Chromosome 22q11.2 deletion syndrome
76Chromosome 22q11.2 duplication syndrome
77DiGeorge syndrome
78Chromosome Xp11.23-p11.22 duplication syndrome
79Chromosome Xp11.3 deletion syndrome
80Chromosome Xp21 deletion syndrome
81Chromosome Xq21 deletion syndrome
82Chromosome Xq22.3 telomeric deletion syndrome
83Chromosome Xq27.3-q28 duplication syndrome
84Chromosome Xq28 deletion syndrome
Important — Who cannot take this test

Due to current technological limits.

  • !Multiple pregnancy (even if fetal reduction occurs at a later stage).
  • !Twin pregnancy that underwent fetal reduction after 8 weeks of gestation.
  • !Fetal reduction within the past 8 weeks.
  • !Pregnant woman or her spouse with known chromosomal disorders.
  • !Pregnancy with placental mosaicism.
  • !Pregnant woman with a Robertsonian translocation fetus.
  • !Pregnancy of less than 10 weeks.
Consult your doctor

Cases that need physician guidance before testing.

  • ✓Allogeneic blood transfusion within the last year.
  • ✓Transplant surgery or stem cell therapy.
  • ✓Cellular immunotherapy introducing exogenous DNA within the past 4 weeks.
  • ✓Abnormal paternal karyotype, or maternal karyotype with qh±, ps±, pstk±, pss.
  • ✓Maternal BMI > 40.
  • ✓History of malignant or benign tumor.
  • ✓Heparin or heparin-analogue therapy.
Frequently asked questions

Common questions, clearly answered.

The health of your child is the most important conversation you'll have.

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