NIFTY®
Test Content

Everything that NIFTY® PRO screens for, in one place.Now, available in the UAE.

Powered by BGI genomics, NIFTY® PRO screens across all 23 pairs of chromosomes. Each sample is sequenced to a depth of 25M, increasing detection of microdeletions and microduplications. 

  • Detects chromosomal disorders across 23 pairs of chromosomes.
  • 25M data per sample for greater micro-event sensitivity.
  • From week 10 of pregnancy, single small blood draw.
NIFTY® PRO Reassures You

Peace of mind, from a single blood draw.

Being pregnant is something every woman is extremely excited for — and naturally, you want to make sure your baby is healthy. Prenatal screening helps you understand whether your baby may have inherited a genetic condition. NIFTY® PRO uses the mother's peripheral blood to accurately assess the risk of Down syndrome and other chromosomal disorders, with no risk to mother or fetus.

Expectant mother resting peacefully — NIFTY® PRO non-invasive fetal trisomy test
23
Pairs of chromosomes screened
25M
Sequencing data per sample
84
Microdeletion / duplication syndromes
Comparison

What each test screens for

A side-by-side of NIFTY® BASIC and NIFTY® PRO — as published by NIFTY®.

Chromosome abnormalityNIFTY®BasicNIFTY® PROMost complete
Trisomies
Down Syndrome — Trisomy 21
Edwards Syndrome — Trisomy 18
Patau Syndrome — Trisomy 13
Rare autosomal aneuploidies (singleton only)
Trisomy 9
Trisomy 16
Trisomy 22
Sex chromosome aneuploidies (singleton only)
Turner Syndrome — 45,X (XO)
Klinefelter Syndrome — XXY
Triple X Syndrome — XXX
XYY Syndrome
Gender Identification
Microdeletion & microduplication syndromes
84 syndromes across all 23 chromosome pairs
Technology

Genomics-grade sequencing, clinically validated.

An Emirati laboratory scientist operating a DNA sequencer
  • Blood sampling is safe, convenient, and entirely non-invasive.
  • High-throughput sequencing covering 95+18 tests and additional findings.
  • High-quality QC monitoring of cell-free fetal DNA concentration.
  • Clinically validated for twin pregnancies.

International certification

  • •International patented analysis — PCT/CN2011/001070
  • •50+ peer-reviewed international clinical papers
  • •Reported by in UAE
NIFTY®BasicNIFTY®Pro
Trisomies

The three most common autosomal trisomies.

Down Syndrome — Trisomy 21

Incidence · Risk increases with maternal age (age 35: 1/400).

Caused by an extra copy of chromosome 21. Most children have intellectual disabilities ranging from mild to moderate; early intervention is essential.

Sensitivity >99.99% · Specificity >99.97%

Edwards Syndrome — Trisomy 18

Incidence · 1 / 6,000

Three copies of chromosome 18. High risk of miscarriage; most babies do not survive beyond the first year. Severe intellectual disabilities and birth defects of the heart, brain, and kidneys.

Sensitivity >99.99% · Specificity >99.97%

Patau Syndrome — Trisomy 13

Incidence · 1 / 10,000 – 1 / 21,700

Three copies of chromosome 13. High risk of miscarriage or stillbirth; heart defects, brain or spinal cord problems, cleft lip/palate, and other birth defects are common.

Sensitivity >99.99% · Specificity >99.96%

NIFTY®Pro
Rare Autosomal Aneuploidies

Going beyond the basics with NIFTY PRO.

Available for singleton pregnancies only.

Trisomy 9

Incidence · Unknown

Full trisomy 9 is lethal in the first trimester. Mosaic trisomy 9 is associated with developmental delay, cardiac, neurological and skull dysmorphisms.

Rare — sensitivity not yet validated

Trisomy 16

Incidence · 32 / 100,000

Full trisomy 16 is lethal in the first trimester. Mosaic trisomy 16 carries increased risk of delayed growth and cognitive disorder.

Rare — sensitivity not yet validated

Trisomy 22

Incidence · 9 / 1,000,000 – 20 / 100,000

Full trisomy 22 is lethal in the first trimester. Mosaic trisomy 22 may cause intellectual disability, kidney malformation and imbalanced development.

Rare — sensitivity not yet validated

NIFTY®BasicNIFTY®Pro
Sex Chromosome Aneuploidies

X and Y chromosome conditions.

Available for singleton pregnancies only.

Turner Syndrome — 45,X (XO)

Incidence · 1 / 2,000 – 1 / 5,000

Completely or partially missing X chromosome in females. Common traits include shorter stature and underdeveloped ovaries leading to infertility.

Sensitivity >95%

Klinefelter Syndrome — XXY

Incidence · 1 / 500

An extra X chromosome in males. Small testes and low testosterone result in incomplete development of male sexual characteristics and infertility.

Sensitivity >95%

Triple X Syndrome — XXX

Incidence · 1 / 1,000

Additional X chromosome in females. Often asymptomatic; can include learning disabilities and delayed speech, language, or motor development.

Sensitivity >95%

XYY Syndrome

Incidence · 1 / 1,000

Extra Y chromosome in males. Affected individuals are typically very tall; may experience severe acne, learning difficulties, and impulsivity.

Sensitivity >95%

Gender Identification

Incidence · —

Singleton fetal gender identification.

>99%

Microdeletion & Microduplication

84 microdeletion and microduplication syndromes.

NIFTY® PRO's extended panel screens for sub-chromosomal events that standard NIPTs may miss — a more complete genomic picture from a single blood draw.

01Chromosome 1p31 duplication syndrome
02Chromosome 1p32-p31 deletion syndrome
03Chromosome 1p36 deletion syndrome
04Chromosome 1q41-q42 deletion syndrome
05Chromosome 2p12-p11.2 deletion syndrome
06Chromosome 2p16.1-p15 deletion syndrome
07Split-hand/foot malformation 5
08Chromosome 2q31.1 duplication syndrome
09Chromosome 2q31.1 deletion syndrome
10Chromosome 2q35 duplication syndrome
11Holoprosencephaly 6
12Chromosome 3pter-p25 deletion syndrome
13Chromosome 3q13.31 deletion syndrome
14Dandy-Walker syndrome
15Chromosome 3q29 deletion syndrome
16Chromosome 3q29 duplication syndrome
17Wolf-Hirschhorn syndrome
18Chromosome 4q21 deletion syndrome
19Chromosome 4q32.1-q32.2 triplication syndrome
20Cri-du-Chat syndrome
21Chromosome 5q12 deletion syndrome
22Chromosome 5q14.3 deletion syndrome
23Chromosome 6pter-p24 deletion syndrome
24Chromosome 6q11-q14 deletion syndrome
25Chromosome 6q24-q25 deletion syndrome
26CHDM
27Chromosome 7q deletion syndrome
28Chromosome 7q11.23 deletion syndrome
29Chromosome 7q11.23 duplication syndrome
30Chromosome 8p23.1 deletion syndrome
31Chromosome 8p23.1 duplication syndrome
32Chromosome 8q12.1-q21.2 deletion syndrome
33Chromosome 8q22.1 duplication syndrome
34Chromosome 8q22.1 deletion syndrome
35Langer-Giedion syndrome
36Chromosome 9p deletion syndrome
37DiGeorge syndrome 2
38Chromosome 10q22.3-q23.2 deletion syndrome
39Chromosome 10q26 deletion syndrome
40Potocki-Shaffer syndrome
41WAGR syndrome
42WAGRO syndrome
43Jacobsen syndrome
44Chromosome 12q14 microdeletion syndrome
45Chromosome 13q14 deletion syndrome
46Chromosome 14q11-q22 deletion syndrome
47Frias syndrome
48Chromosome 15q11-q13 duplication syndrome
49Angelman syndrome
50Prader-Willi syndrome
51Chromosome 15q14 deletion syndrome
52Chromosome 15q25 deletion syndrome
53Congenital Diaphragmatic Hernia (CDH)
54Chromosome 15q26-qter deletion syndrome
55Levy-Shanske syndrome
56Chromosome 16p deletion syndrome
57Chromosome 16p11.2-p12.2 microduplication syndrome
58Chromosome 16p12.2-p11.2 deletion syndrome
59Chromosome 16p13.3 deletion syndrome
60Chromosome 16q22 deletion syndrome
61Potocki-Lupski syndrome
62Smith-Magenis syndrome
63Yuan-Harel-Lupski syndrome
64Chromosome 17p13.3 duplication syndrome
65Chromosome 17p13.3 deletion syndrome
66Chromosome 17q12 deletion syndrome
67Chromosome 17q12 duplication syndrome
68Chromosome 17q21.31 duplication syndrome
69Chromosome 17q23.1-q23.2 deletion syndrome
70Chromosome 18p deletion syndrome
71Chromosome 18q deletion syndrome
72Chromosome 19q13.11 deletion syndrome
73Holoprosencephaly 1
74Cat-Eye syndrome
75Chromosome 22q11.2 deletion syndrome
76Chromosome 22q11.2 duplication syndrome
77DiGeorge syndrome
78Chromosome Xp11.23-p11.22 duplication syndrome
79Chromosome Xp11.3 deletion syndrome
80Chromosome Xp21 deletion syndrome
81Chromosome Xq21 deletion syndrome
82Chromosome Xq22.3 telomeric deletion syndrome
83Chromosome Xq27.3-q28 duplication syndrome
84Chromosome Xq28 deletion syndrome
Important — Who cannot take this test

Due to current technological limits.

  • !Multiple pregnancy (even if fetal reduction occurs at a later stage).
  • !Twin pregnancy that underwent fetal reduction after 8 weeks of gestation.
  • !Fetal reduction within the past 8 weeks.
  • !Pregnant woman or her spouse with known chromosomal disorders.
  • !Pregnancy with placental mosaicism.
  • !Pregnant woman with a Robertsonian translocation fetus.
  • !Pregnancy of less than 10 weeks.
Consult your doctor

Cases that need physician guidance before testing.

  • ✓Allogeneic blood transfusion within the last year.
  • ✓Transplant surgery or stem cell therapy.
  • ✓Cellular immunotherapy introducing exogenous DNA within the past 4 weeks.
  • ✓Abnormal paternal karyotype, or maternal karyotype with qh±, ps±, pstk±, pss.
  • ✓Maternal BMI > 40.
  • ✓History of malignant or benign tumor.
  • ✓Heparin or heparin-analogue therapy.
Frequently asked questions

Common questions, clearly answered.

The health of your child is the most important conversation you'll have.

Book a consultation